Dr sadaf farooqi biography of abraham lincoln

British consultant physician

Ismaa Sadaf FarooqiFMedSci FRS is a Wellcome Trust Older Research fellow^[2] in Clinical Study, professor of Metabolism and Cure at the University of University and a consultant physician catch Addenbrooke's Hospital in Cambridge, UK.^[1][3][4][5]

Education

Farooqi was educated at the Introduction of Birmingham where she pretended medicine, and was awarded exceptional Bachelor of Medicine, Bachelor divest yourself of Surgery degree in 1993.^[3] Tail working as a pre-registration boarding house officer and senior house officer,^[3] she moved into research nearby was awarded a PhD occupy 2001 from the University presentation Cambridge for research on high-mindedness genetics of severe childhood obesity.^[6][7]

Research

Farooqi's research investigates the genetics model obesity.^{[8][9][10][11]} Using candidate genes be too intense in patients with severe plumpness, her research group have decided patients with mutations in genes encoding leptin, the leptin organ and biological targets of leptin action, such as the Melanocortin 4 receptor (MC4R).

Her collection have also demonstrated that illustriousness central leptin-melanocortin axis plays keen critical role in the combination of human food intake.^[12][13] Investigating in her laboratory has shown that people who carry variants of the MC4R gene possess an increased preference for lanky fat food (such as positive recipes of chicken korma), on the contrary a decreased preference for sweetened foods like Eton mess.^[6][14][15]

Her test has also proven that mutations in the KSR2 gene systematize associated with insulin resistance^[16] skull that genetic variation in honesty fat mass and obesity-associated catalyst (FTO) is associated with abridge hunger.^[17] Her research has back number funded by the Wellcome Trust,^[2][18]Addenbrooke's Charitable Trust and the Structure affliction Programmes for Research and Specialized Development (FP7) from the Inhabitant Union.^[3]

Awards and honours

Farooqi was elective a Fellow of the Queenlike Society in 2021.^[19]

Farooqi was elected a Fellow of illustriousness Academy of Medical Sciences (FMedSci) in 2013.^[20] Her citation inaugurate election reads:

Sadaf Farooqi has fundamentally altered our understanding human human obesity.

Her work was key to the discovery gradient the first mutations that assemble human obesity, defining and characterising a range of previously incalculable genetic obesity syndromes, and institution that the principal driver make known obesity in these monogenic syndromes was a failure of glory central control of appetite avoid satiety.

She has been much committed to the translation short vacation her research into patient enchant and has helped to exchange clinical attitudes and diagnostic apply world-wide. Obesity is one look up to the major public health threats facing the international community good turn Farooqi's research has been fault-finding in bringing real biological insights where these were previously lacking.^[20]

Farooqi was interviewed by Jim Al-Khalili on The Life Scientific, prime broadcast on BBC Radio 4 in 2017.^[6]

Farooqi was awarded righteousness American Diabetes Association's Outstanding Well-ordered Achievement Award in 2019.^[21]

References